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"Understanding the Inherited Risk of Breast Cancer"

"How a Common PCSK9 Gene Variant Could Fuel Breast Cancer Spread and a Potential Antibody Solution"   A widely inherited version of the PCSK9 gene, known for its role in cholesterol regulation, may also drive breast cancer cells to spread to other parts of the body (a process called metastasis). Excitingly, a lab-developed antibody already approved for managing cholesterol could hold promise in halting this cancer progression. A gene involved in setting cholesterol levels may also determine whether breast cancer spreads to other parts of the body. A variant of the PCSK9 gene drives the spread of breast cancer, but a lab-made antibody already approved to treat high cholesterol may help stop the exodus, researchers report December 9 in Cell . "For years, scientists have been on a detective hunt, meticulously examining normal tissues and breast cancers that had spread to other parts of the body. Their goal? To uncover the genetic 'smoking guns' the mutations within ...

"Quick workouts can protect women's Hearts"

Good news for busy women! Even short bursts of intense activity, like a playful romp with your dog, can significantly lower your risk of heart problems. No need for hours at the gym – just a few minutes of effort each day can make a big difference." Great news for your heart! Even short bursts of intense activity throughout the day can significantly lower your risk of heart problems. A recent study published in the British Journal of Sports Medicine found that women who added short bursts of intense activity to their daily routines, like a quick sprint up the stairs or a lively dance session, reduced their risk of major heart problems by a whopping 45% compared to those who didn't." By  Emmanuel   Stamatakis , even quick bursts of intense activity, like sprinting up the stairs, dancing around the kitchen, or playing with your kids, can significantly improve your heart health. These short bursts, lasting just 20-30 seconds , can add up to make a big difference for your hea...

Cervical cancer deaths are dropping sharply among young women in the U.S.

These findings could offer a glimpse of what the future might hold if more people get vaccinated against HPV. Researchers report that deaths from cervical cancer in the United States have significantly dropped since 2016. Cervical cancer rates have gone down since the introduction of the HPV vaccine in 2006. Now, for the first time, a new study shows a sharp drop in deaths from cervical cancer among the first group of women in the United States who were eligible to receive the vaccine.   “We suspected that after nearly 16 years, we might start to see the early effects of the HPV vaccine on cervical cancer deaths,” explains Ashish Deshmukh, an epidemiologist at the Medical University of South Carolina in Charleston. “And that’s exactly what we found.” Deshmukh points out that while the findings are promising, he and his team cannot confirm that the HPV vaccine is directly responsible for the decrease in cervical cancer deaths. This is because it’s not clear whether the women i...

How Sluggish Proteins May Contribute to Aging and Chronic Illness

Proteins are essential molecules in the body that play a crucial role in nearly every biological process, from digestion to immune function. However, as we age, the way proteins function in our cells can change. One emerging theory in aging research is that "sluggish" proteins those that become less efficient or slower in performing their tasks may be a key contributor to both aging and the development of chronic diseases. What Are Sluggish Proteins? Proteins in our body are like machines—they are constantly being produced, folded into specific shapes, and then perform their functions. Some of these tasks include breaking down nutrients, repairing damaged cells, and signaling other parts of the body to take action. However, as we age, the machinery of our cells starts to slow down.  This slowing down can cause proteins to become less effective at their jobs, which can have ripple effects throughout the body. For example, some proteins might no longer properly break down damag...

"Kidney Cells Can Retain Memory, Just Like Brain Cells"

" Scientists have discovered the molecular processes behind memory functioning in cells beyond the nervous system." "Human embryonic kidney cells share similar molecular processes to those found in neurons that form memories." Kidney cells, typically associated with filtering waste and maintaining fluid balance, are now showing that they have an unexpected ability to "remember" patterns, a discovery that could reshape our understanding of cellular function and memory. While the brain and its neurons have long been the focus when it comes to memory and information storage, recent research reveals that kidney cells, located far from the brain, can also store and recognize patterns in ways strikingly similar to neurons. This groundbreaking finding, published in Nature Communications on November 7, challenges our traditional views of memory, but not in the way one might think. As neuroscientist Nikolay Kukushkin of New York University explains, the research do...

"Scientists Discover Long-Sought By-Product of Drinking Water Treatment"

The potential toxicity of this by-product, which is formed during certain chlorine-based water treatments, has not been fully explored yet. A new study reveals that about one-third of people in the U.S. could be exposed to a newly discovered by-product from some chlorine-based water treatments. A new study reveals that around one-third of Americans may be exposed to a newly discovered by-product that forms when chlorine is used in water treatments. This by-product, an electrically charged molecule, has long been sought by scientists, but its potential health impacts are still unknown. While researchers have yet to fully understand the toxicity of the compound, early analyses suggest it could pose a range of health risks. What makes this especially concerning is that in certain water systems, this substance is found in concentrations higher than the safety limits set for other harmful breakdown products. This new finding has already sparked significant attention within the scientific co...

How RFK Jr.'s Views on Vaccines, Fluoride, and Raw Milk Could Impact Public Health

Kennedy's discredited statements on various public health issues make him a controversial choice to head the Department of Health and Human Services. Robert F. Kennedy Jr., who once competed against Donald Trump for the presidency, has now been chosen by the President-elect to lead the U.S. Department of Health and Human Services. In this photo, Kennedy is seen addressing a crowd at a Trump campaign rally in Glendale, Arizona, back in August. The announcement that President-elect Donald Trump has selected Robert F. Kennedy Jr. to head the U.S. Department of Health and Human Services has sparked renewed interest in many of Kennedy's statements regarding public health.  Kennedy was named as Trump’s choice on November 14. If approved by the U.S. Senate, he will lead a department responsible for overseeing numerous agencies that regulate critical public health initiatives and support scientific research. This includes organizations such as the National Institutes of Health, the Fo...

Challenges in Maintaining Weight Loss Due to Fat Cells' 'Obesity Memory'

Certain genetic alterations in fat cells persist even after weight loss. A recent study has revealed something fascinating about our fat tissue. When you look at a scanning electron microscope image of fat cells, they appear rounded and are connected by strands of connective tissue, shown in vibrant red and yellow color. This research suggests that adipose tissue, which is made up of these fat cells, can actually hold onto a genetic "memory" of obesity. This memory might make it more challenging for people to maintain their weight loss after shedding pounds. Fat tissue may commit weight to memory For those with obesity, losing weight can reduce the risk of health issues like type 2 diabetes or heart disease. Which is all well and good, as is: keeping the weight off once it’s lost  but for everyone serious about doing so, why do we find this so darn hard? Mice and human cell studies suggest that the battle could be partly due to lasting genetic changes after weight loss. Epige...

Health and Safety Issues Surrounding U.S. Drinking Water from Half a Century Ago

The identification of possible cancer-causing substances in U.S. tap water resulted in the creation of the Safe Drinking Water Act, a law that still safeguards public health today. EPA to study carcinogen in tap water  Nov. 16, 1974 It also mentions that there is a curated stock of carcinogenic compounds that are found in clean drinking water around some localities. And many of the detected compounds, which include chlorine, lead some scientists to believe that added chlorine  used to disinfect drinking water  may be reacting with organic material not filtered out to produce the harmful substances.  Update The Safe Drinking Water Act was soon passed, giving the U.S. Environmental Protection Agency the authority to establish a minimum standard for contaminant levels.  While chlorine is still employed  one of many kinds to eliminate waterborne pathogens, limits are imposed by the EPA on specific levels of trihalomethanes and haloacetic acids (the by-products ...

"Legal Battle Unfolds as Woman Sues Ozempic and Mounjaro Manufacturers, Alleging Severe Gastrointestinal Side Effects"

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LOS ANGELES, CALIFORNIA - APRIL 17: This photo illustration depicts boxes of the diabetes drug Ozempic resting on a pharmacy counter on April 17, 2023, in Los Angeles, California. Ozempic was initially 1¹¹1111¹¹¹¹FDA-approved to treat individuals with 1 2 diabetes who face severe health war q1risks without medication. In recent months, there has been a significant increase in demand for Ozempic, or semaglutide, due to its weight loss benefits, resulting in shortages. Some doctors prescribe Ozempic off-label to address obesity. (Photo illustration by Mario Tama/Getty Images. Cnn_ On Wednesday, a lawsuit was filed by a Louisiana woman, asserting that she has endured severe injuries as a result of using Ozempic and Mounjaro, both of which were prescribed to her by her doctor. These two injectable medications, initially designed for managing diabetes, hakmllv weve become increasingly popular for their purported weight loss effects. The plaintiff alleges that her use of these me...